Hemophagocytic lymphohistiocytosis after certolizumab treatment in a patient with rheumatoid arthritis


Guven G., Guler A., ÖZYÜNCÜ N., TALAN L., HEPER A., TURGAY T. M., ...Daha Fazla

EUROPEAN JOURNAL OF RHEUMATOLOGY, cilt.5, sa.3, ss.203-205, 2018 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/eurjrheum.2018.17108
  • Dergi Adı: EUROPEAN JOURNAL OF RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.203-205
  • Anahtar Kelimeler: Hemophagocytic lymphohistiocytosis, rheumatoid arthritis, certolizumab, skin involvement, DISEASE, INFLIXIMAB
  • Ankara Üniversitesi Adresli: Evet

Özet

Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening syndrome that may be triggered by hereditary factors, autoimmune and immunologic disorders, infectious diseases, malignancies and medications. Suspicion of the disease and early treatment is of paramount importance. Since the presentation of HLH with only skin involvement is rare, early diagnosis may be difficult. A pathologically confirmed HLH case that presented with maculopapular skin lesions after certolizumab treatment is being reported in this presentation.