Lateral flow assays for toxins, metabolites, and beyond
Lateral Flow Assays: From Bench to Market, Elsevier, ss.393-432, 2025
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2025
- Doi Numarası: 10.1016/b978-0-443-23883-3.00010-6
- Yayınevi: Elsevier
- Sayfa Sayıları: ss.393-432
- Anahtar Kelimeler: Biosensing, Drugs and drug metobolites sensing, Lateral flow assays, Mycotoxin analysis, Rapid analysis, Toxins detection
- Ankara Üniversitesi Adresli: Evet
Özet
The most popular point-of-care biosensors for diagnostic, biomedical, food, agricultural, and environmental applications are lateral flow assays (LFAs). While the fundamentals of lateral flow assay technology date back several decades, newer nanomaterials have been employed as receptor attachment platforms or signal transducers, enhancing analytical capabilities. The recent development of LFAs illustrates their promising features, including their capacity to analyze several analytes and their speed, precision, dependability, and affordability for detecting toxins and metabolites. With their connection to smartphone technologies, they present an encouraging technological tool for point-of-care analysis, mobile medical services, and bioanalytical requirements. This chapter presents the LFAs for toxins and metabolites, investigates the construction protocol of LFAs, sensitivities and detection limits of LFAs, and limitations in complex sample applications. In addition, the challenges facing the next generation of LFAs and their commercialization are emphasized. Furthermore, this chapter will stimulate further study to create sophisticated, multifunctional, and integrated LFA for different applications.