Adrenomedullin and total nitrite levels in children with familial Mediterranean fever

Balat A., Islek I., ÇEKMEN M. B., Yurekli M., TEKİN D., Muslu A., ...Daha Fazla

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, cilt.42, sa.5, ss.240-243, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1440-1754.2006.00845.x
  • Dergi Adı: JOURNAL OF PAEDIATRICS AND CHILD HEALTH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.240-243
  • Anahtar Kelimeler: adrenomedullin, familial Mediterranean fever, nitric oxide, TUMOR-NECROSIS-FACTOR, HYPOTENSIVE PEPTIDE, MESANGIAL CELLS, OXIDE SYNTHASE, MESSENGER-RNA, INTERLEUKIN-1, EXPRESSION, PATHWAY, ROLES
  • Ankara Üniversitesi Adresli: Hayır

Özet

Aim: Familial Mediterranean fever (FMF) is the most frequent periodic syndrome characterised by recurrent attacks of polyserositis. However, recent studies revealed that there might be an ongoing subclinical inflammation between the attacks. As nitric oxide (NO) and adrenomedullin (AM) are both synthesised in the endothelium, and mediates many functions within immune system, we considered them to be an interesting target of investigation in FMF.