The confounding effect of interleukin-6 on apoptosis of MCF-7 cells through downregulation of MMP-2/-9 mRNA expression
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.46, sa.5, ss.549-555, 2021 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 5
- Basım Tarihi: 2021
- Doi Numarası: 10.1515/tjb-2020-0508
- Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, Food Science & Technology Abstracts, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.549-555
- Anahtar Kelimeler: apoptosis, interleukin-6, MCF-7, MMP-2/-9, proliferation, SIGNALING PATHWAY, ONCOSTATIN-M, GROWTH, IL-6, IMMUNOTHERAPY, IMMUNITY
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
Objectives: Breast cancer is the second cause of death among women worldwide. In the last decades, the immunotherapy-based approaches have a growing importance in the treatment of breast cancer. Several studies have indicated the pleiotrophic effect of Interleukin-6 (IL-6) via targeting the membrane-bound or soluble receptors.