Y-chromosome and autosomal STR diversity in four proximate settlements in Central Anatolia

Alakoc Y., Gokcumen O., Tug A., GÜLTEKİN T., Gulec E., Schurr T. G.

FORENSIC SCIENCE INTERNATIONAL-GENETICS, cilt.4, sa.5, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4 Sayı: 5
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.fsigen.2010.01.016
  • Dergi Adı: FORENSIC SCIENCE INTERNATIONAL-GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Forensics, DNA typing, Population genetics, Turkey, Heterozygosity, Gene diversity, Patrilineage, DYS19, DYS385a, DYS385b, DYS388, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS439, DYS448, DYS456, DYS458, DYS635, H4-YGATA, D8S1179, D21S11, D7S820, CSF1P0, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, Amelogenin, D5S818, FGA
  • Ankara Üniversitesi Adresli: Evet

Özet

Due to the longstanding human presence in the region and the influence of social traditions, the genetic make-up of populations currently inhabiting Turkey (Anatolia) is quite complex. To characterize the patterns of genetic diversity in rural Central Anatolian villages, we analyzed samples collected at four local settlements for variation at 17 Y-chromosome STR and 15 autosomal STR loci. The resulting data reveal considerable diversity within these settlements, as well as some structure in the paternal genetic variation, with a limited number of haplotypes being shared between the communities. These findings have important implications for forensic studies of Turkish populations. (C) 2010 Elsevier Ireland Ltd. All rights reserved.