Mathematical modeling of a packed bed bioreactor for the citric acid production
REVIEWS IN CHEMICAL ENGINEERING, cilt.15, sa.4, ss.279-292, 1999 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 15 Sayı: 4
- Basım Tarihi: 1999
- Doi Numarası: 10.1515/revce.1999.15.4.279
- Dergi Adı: REVIEWS IN CHEMICAL ENGINEERING
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.279-292
- Anahtar Kelimeler: citric acid production, immobilized Aspergillus niger, packed bed bioreactor, axial dispersion, modeling, ENZYME REACTORS, PERFORMANCE, FLOW
- Ankara Üniversitesi Adresli: Evet
Özet
Design parameters of a packed bed bioreactor used for citric acid production by immobilized Aspergillus niger microorganisms were investigated. The consumption rate of sucrose in citric acid production process was observed to follow substrate activation kinetics. The use of Marquartdt-Levenberg software package yielded the apparent kinetic parameters as r(Smax)= 1,808x10 (-6) kg/kg particle. s, K-1=153 kg/m (3) and K-2 =1315 kg/m (3). The maximum citric acid production yield, by this packed bed bioreactor system was 0,344 g/l/h. In this study a mathematical model was also developed and tested with the experimental results. This model involves axial convection and dispersion, as well as interphase film mass transfer and chemical reaction. The governing equations were simultaneously solved by a Fortran code (Colmod) using the Orthogonal Collogation Method. Model predictions, when compared to experimental results, demonstrated that axial dispersion took maximum effect at the column entrance. The model was also solved for the larger Peclet numbers (similar to 1000) for which the system approaches to plug flow conditions. Nevertheless, the predictions were found to be in good agreement with the experimental results when the axial dispersion was taken into account.