Akademik Veri Yönetim Sistemi
ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.63, sa.4, ss.401-406, 2016 (SCI-Expanded)
In this study, juvenile common carp (Cyprinus carpio) were subjected to sublethal concentrations of the synthetic pyrethroids cypermethrin (2 mu g/L) and cyphenothrin (5 mu g/L) for 75 days. The toxic effects of these substances were analyzed pathomorphologically by conducting necropsies on 7 fish on days 15, 30, 45, 60, and 75. In addition, histopathological examination of the gonads was performed by exposing to 17 beta-estradiol (E2) (25 mu g/L) as a positive control group to assess the endocrine disrupting effects of cypermethrin and cyphenothrin. Hyperemia, telangiectasia, epithelial lifting, and branchitis were observed in the gills of the fish from both treatment groups, and hemorrhage in the kidneys and hyperemia in the brain were also detected. Only 1 fish from each of the cypermethrin and E2 groups was observed to have degeneration of the testicles and edema of the ovary. One fish from the cyphenothrin group had degeneration of the testicles and another had oophoritis of the ovary. Based on the hyperemia and telangiectasia observed in the gills, it was concluded that both cypermethrin and cyphenothrin may lead to shortness of breath in these fish. However, only minor lesions were detected in the gonads; thus, there was no evidence that these synthetic pyrethroids affect the endocrine system.