Akademik Veri Yönetim Sistemi
Sunum, ss.1-26, 2025
Abstract
Background Oral squamous carcinoma (OSCC) is often diagnosed at late stages and bone erosion or invasion of the
jawbone is frequently present. Computed tomography (CT) and magnetic resonance imaging (MRI) are known to
have high diagnostic sensitivities, specificities, and accuracies in detecting these bone affections in patients suffering
from OSCC. To date, the existing data regarding the impact of cone-beam computed tomography (CBCT) have been
weak. Therefore, this study aimed to investigate whether CBCT is a suitable tool to detect bone erosion or invasion in
patients with OSCC.
Methods We investigated in a prospective trial the impact of CBCT in the diagnosis of bone erosion or invasion in
patients with OSCC who underwent surgery. Every participant received a CBCT, CT, and MRI scan during staging.
Imaging modalities were evaluated by two specialists in oral and maxillofacial surgery (CBCT) and two specialists
in radiology (CT and MRI) in a blinded way, to determine whether a bone affection was present or not. Reporting
used the following 3-point system: no bony destruction (“0”), cortical bone erosion (“1”), or medullary bone invasion
(“2”). Histological examination or a follow-up served to calculate the sensitivities, specificities, and accuracies of the
imaging modalities.
Results Our results revealed high diagnostic sensitivities (95.6%, 84.4%, and 88.9%), specificities (87.0%, 91.7%, and
91.7%), and accuracies (89.5%, 89.5%, and 90.8%) for CBCT, CT, and MRI. A pairwise comparison found no statistical
difference between CBCT, CT, and MRI.