Evaluation of the level of dynamic thiol/disulphide homeostasis in adolescent patients with newly diagnosed primary hypertension

Cakici, Evrim; Eroglu, Fehime; Yazilitas, Fatma; Bulbul, Mehmet; Gur, Gokce; AYDOĞ, ÖZLEM; Gungor, Tulin; EREL, ÖZCAN; Alisik, Murat; ELHAN, ATİLLA

doi:10.1007/s00467-017-3865-3

Evaluation of the level of dynamic thiol/disulphide homeostasis in adolescent patients with newly diagnosed primary hypertension

Cakici E. K., Eroglu F. K., Yazilitas F., Bulbul M., Gur G., AYDOĞ Ö., ...Daha Fazla

PEDIATRIC NEPHROLOGY, cilt.33, sa.5, ss.847-853, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 33 Sayı: 5
Basım Tarihi: 2018
Doi Numarası: 10.1007/s00467-017-3865-3
Dergi Adı: PEDIATRIC NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.847-853
Anahtar Kelimeler: Oxidative stress, Dynamic thiol/disulphide, Oxidized thiol, Blood pressure, Adolescents, BLOOD-PRESSURE, OXIDATIVE STRESS, PLASMA, SUPPLEMENTATION, PATHOGENESIS, CHILDREN
Ankara Üniversitesi Adresli: Evet

Özet

Background Thiol/disulphide homeostasis plays a critical role in numerous intracellular enzymatic pathways including antioxidant defense and detoxification. This study was designed to investigate the impact of thiol/disulfide homeostasis in adolescent patients with recently diagnosed primary hypertension (HT) using a novel and automated method.