Effects of levetiracetam and valproic acid treatment on liver function tests, plasma free carnitine and lipid peroxidation in childhood epilepsies

Haznedar P., DOĞAN Ö., Albayrak P., Tuncer G. O., TEBER S., Deda G., ...Daha Fazla

EPILEPSY RESEARCH, cilt.153, ss.7-13, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 153
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.eplepsyres.2019.03.009
  • Dergi Adı: EPILEPSY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.7-13
  • Anahtar Kelimeler: Carnitine, Epilepsy, Levetiracetam, Oxidative stress, Valproic acid, 8-OHdG, INCREASED OXIDATIVE STRESS, ANTIEPILEPTIC DRUGS, POSTSTROKE SEIZURES, DNA-DAMAGE, CHILDREN, MONOTHERAPY, CARBAMAZEPINE, MANAGEMENT, LEVEL
  • Ankara Üniversitesi Adresli: Evet

Özet

Background and aims: The relationship between anti-epileptic usage and oxidative damage has not yet been clearly understood. In our study, we investigated oxidative stress parameters, carnitine levels, liver function tests (LFT) and their relationship in epileptic children treated with valproic acid or levetiracetam.