Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data meta-analysis.


Huang D. Q., Noureddin N., Ajmera V., Amangurbanova M., Bettencourt R., Truong E., ...Daha Fazla

The lancet. Gastroenterology & hepatology, cilt.8, sa.9, ss.829-836, 2023 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 9
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/s2468-1253(23)00157-7
  • Dergi Adı: The lancet. Gastroenterology & hepatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Food Science & Technology Abstracts, MEDLINE
  • Sayfa Sayıları: ss.829-836
  • Ankara Üniversitesi Adresli: Evet

Özet

We propose a supergravity inspired derivation of a Randall-Sundrum's type action as an effective description of the dynamics of a brane coupled to the bulk through gravity only. The cosmological constants in the bulk and on the brane appear at the classical level when solving the equations of motion describing the bosonic sector of supergravities in ten and eleven dimensions coupled to the brane. They are related to physical quantities like the brane electric charge and thus inherit some of their physical properties. The most appealing property is their quantization: in d_\perp extra dimensions, Lambda_brane goes like N and Lambda_bulk like N^{2/(2-d_perp)}. This dynamical origin also explains the apparent fine-tuning required in the Randall-Sundrum scenario. In our approach, the cosmological constants are derived parameters and cannot be chosen arbitrarily; instead they are determined by the underlying Lagrangian. Some of the branes we construct that support cosmological constant in the bulk have supersymmetric properties: D3-branes of type IIB superstring theory provide an explicit example.