Functional Neurology, vol.7, no.6 SUPPL., pp.15-16, 1992 (SCI-Expanded)
Patients with recurrent headache often describe a history that includes frequent use of medications, such as analgesics, barbiturates, benzodiazepines, opiates, caffeine, ergot derivatives or their combinations. Because many diverse substances may be abused in headache patients, the causes and mechanisms may be different. The mechanism of drug-induced headache is not known. There is evidence to suggest that drug-induced headache may be restricted to those with primary headache disorders, especially migraineurs.