EPIDEMIOLOGY AND CLINICAL OUTCOME OF HEPATITIS-D VIRUS-INFECTION IN TURKEY

BALIK İ., ONUL M., TEKELI E., CAREDDA F.

EUROPEAN JOURNAL OF EPIDEMIOLOGY, cilt.7, sa.1, ss.48-54, 1991 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 1
  • Basım Tarihi: 1991
  • Doi Numarası: 10.1007/bf00221341
  • Dergi Adı: EUROPEAN JOURNAL OF EPIDEMIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.48-54
  • Anahtar Kelimeler: HDV EPIDEMIOLOGY, HDV INFECTION, DELTA HEPATITIS
  • Ankara Üniversitesi Adresli: Evet

Özet

The prevalence, the epidemiology, the clinical and biochemical characteristics of hepatitis delta virus (HDV) infection were studied in patients with HBsAg-positive acute hepatitis, in those with chronic liver disease, and in apparently healthy carriers in Turkey. Fifty-eight of the 242 carriers of HBsAg (23.9%) and 31 of the 237 (13.1%) patients with acute HBsAg-positive hepatitis had serological evidence of HDV infection. Eleven of these individuals were HBsAg carriers with acute HDV superinfection. The prevalence of HDV infection was significantly (p < 0.001) higher in patients with chronic liver disease (54/165; 32.7%) than in asymptomatic carriers of HBsAg (4/77; 5.2%). The highest prevalence (26/57; 45.6%) of HDV infection was found in patients at high risk of acquiring hepatitis virus infection (health care workers, hemodialysis patients, polytransfused patients) with chronic liver disease.