Bisphenols emerging in Norwegian and Czech aquatic environments show transthyretin binding potency and other less-studied endocrine-disrupting activities

Sauer P., Svecova H., Grabicova K., Aydin F. G., Mackulak T., Kodes V., ...More

SCIENCE OF THE TOTAL ENVIRONMENT, vol.751, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 751
  • Publication Date: 2021
  • Doi Number: 10.1016/j.scitotenv.2020.141801
  • Journal Name: SCIENCE OF THE TOTAL ENVIRONMENT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Analytical Abstracts, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, Geobase, Greenfile, MEDLINE, Metadex, Pollution Abstracts, Public Affairs Index, Veterinary Science Database, Civil Engineering Abstracts
  • Keywords: Bisphenol analogs, Occurrence, Pollution, Industrial chemicals, Hormonal activity, WATER TREATMENT PLANTS, BROMINATED FLAME RETARDANTS, WASTE-WATER, SEWAGE-SLUDGE, SURFACE-WATER, HUMAN EXPOSURE, COMPETITIVE INTERACTIONS, MS/MS METHOD, TAIHU LAKE, ANALOGS
  • Ankara University Affiliated: Yes

Abstract

Bisphenols are increasingly recognized as environmental pollutants with endocrine-disrupting potential. Nonetheless, the study of environmental occurrence and some endocrine-disrupting activities of some bisphenols came widely into focus of research only recently. The aims of the present study were to: 1) determine the predominant bisphenols in Norwegian sewage sludge and sediment and in Czech surface waters, and 2) characterize the binding of bisphenols to a transport protein transthyretin (TTR) and their (anti-)thyroid, (anti-) progestagenic, and (anti-)androgenic activities.