Are optical coherence tomography and fluorescein angiography comparable for detection of macular edema in Behçet uveitis?


Değirmenci M. F. K., YALÇINDAĞ F. N.

Graefe's Archive for Clinical and Experimental Ophthalmology, cilt.261, sa.11, ss.3275-3281, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 261 Sayı: 11
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s00417-023-06249-0
  • Dergi Adı: Graefe's Archive for Clinical and Experimental Ophthalmology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.3275-3281
  • Anahtar Kelimeler: Behçet uveitis, Fluorescein angiography, Macular edema, Macular leakage, Spectral domain-optical coherence tomography
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose: To investigate the role and agreement of spectral domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) for macular edema (ME) diagnosis in Behçet uveitis (BU). Methods: Eyes with ME detected by SD-OCT and/or FA were enrolled. Type of ME by SD-OCT and grade of macular leakage (ML) by FA were investigated. Eyes were divided into three groups according to the agreement of tests. Three groups and factors that could affect the compatibility of tests were statistically analyzed. Results: Sixty-one eyes of 61 patients were included. Both imaging methods detected ME in 42.6% of eyes (group 1). In 47.5% of eyes, ME was revealed by OCT (group 2). The remaining 9.8% of the eyes had ME, detected only by FA (group 3). Grade 2 ML by FA was more common in group 1 (p = 0.01). The grade of ML by FA was similar in groups 2 and 3. In group 2, most of the eyes showed diffuse ME by OCT (p < 0.001). Epiretinal membrane was detected more frequently in group 3 (p = 0.005). Duration and activity of uveitis were similar between groups. Conclusion: SD-OCT was able to detect ME in 90% of the eyes with BU. Duration and activity of uveitis were not related to the compatibility of imaging methods.