Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates

Bayraktutar B. N., Ucakhan Ö. Ö.

CASE REPORTS IN OPHTHALMOLOGY, cilt.7, sa.1, ss.135-140, 2016 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1159/000444784
  • Dergi Adı: CASE REPORTS IN OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.135-140
  • Anahtar Kelimeler: Adenoviral keratoconjunctivitis, Cyclosporine A, Subepithelial infiltrates, EYE
  • Ankara Üniversitesi Adresli: Evet

Özet

Subepithelial infiltrates secondary to adenoviral keratoconjunctivitis may persist for years and cause blurred vision, halos, glare, and photophobia. These infiltrates arise from immune reaction against the virus, and few studies have reported topical cyclosporine A to be effective in the treatment of subepithelial infiltrates. Herein, we describe a patient with adenoviral keratoconjunctivitis-related subepithelial infiltrates who did not respond to treatment with a new topical cyclosporine A emulsion prepared with castor oil (Depores 0.05%; Deva Ilac, Kocaeli, Turkey), while the FDA-approved nanoemulsion formulation provided improvement in symptoms and reduced the inflammatory reaction (Restasis 0.05%; Allergan, Irvine, Calif., USA). (C) 2016 The Author(s) Published by S. Karger AG, Basel