Rosai-Dorfman disease presenting as mediastinal lymphadenopathy: Case report and review of the literature

Cobanoglu N., GALİP ÇELİK N., DALKAN C., Comunoglu C., BAHÇECİLER N.

Paediatrics and International Child Health, cilt.33, sa.2, ss.120-123, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1179/2046905512y.0000000025
  • Dergi Adı: Paediatrics and International Child Health
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.120-123
  • Anahtar Kelimeler: Mediastinal lymphadenomegaly, Rosai-Dorfman disease, Immune deficiency, Corticosteroids, Intravenous immunoglobulin, Emperipolesis, FINE-NEEDLE-ASPIRATION, MASSIVE LYMPHADENOPATHY, SINUS HISTIOCYTOSIS, ENTITY
  • Ankara Üniversitesi Adresli: Evet

Özet

A 6-year-old boy presented with recurrent pneumonia and diarrhoea for 3 years. He had extensive mediastinal lymphadenopathy and atelectasis with low serum levels of IgA, IgG and IgG3. An inguinal lymph node biopsy demonstrated histological and histochemical features of Rosai-Dorfman disease. There was emperipolesis and histiocytes were immune-positive for S100 proteins. He responded to corticosteroids and regular infusions of immunoglobulins. © W. S. Maney & Son Ltd 2013.