DNA Copy Number Changes in Gastric Adenocarcinomas: High Resolution-Comparative Genomic Hybridization Study in Turkey

GÜMÜŞ AKAY, GÜVEM; ÜNAL, ALİ; ELHAN, ATİLLA; BAYAR, SANCAR; Karadayt, Kuersat; SUNGUROĞLU, ASUMAN; Kadikiran, Ahmet; Tukun, Ajlan

doi:10.1016/j.arcmed.2009.07.004

DNA Copy Number Changes in Gastric Adenocarcinomas: High Resolution-Comparative Genomic Hybridization Study in Turkey

GÜMÜŞ AKAY G., ÜNAL A. E., ELHAN A. H., BAYAR S., Karadayt K., SUNGUROĞLU A., ...Daha Fazla

ARCHIVES OF MEDICAL RESEARCH, cilt.40, sa.7, ss.551-560, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 40 Sayı: 7
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.arcmed.2009.07.004
Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.551-560
Anahtar Kelimeler: Genomic imbalances, High-resolution-comparative genomic hybridization, Gastric adenocarcinoma, Tumor progression, GENETIC ALTERATIONS, HISTOLOGIC SUBTYPES, PRECURSOR LESIONS, TUMOR PROGRESSION, POOR-PROGNOSIS, CELL-LINES, CANCER, EXPRESSION, CARCINOMA, RCAS1
Ankara Üniversitesi Adresli: Evet

Özet

Background and Aims. Multiple genetic alterations are responsible for development and progression of gastric cancer which is one of the leading causes of cancer-related deaths worldwide. The aim of this study was to identify the genomic imbalances of gains and/or losses in gastric adenocarcinomas from Turkish patients and to investigate their association with development and progression of this type of cancer.