IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines

Zhu, XingWu; Mulcahy, Lori; Mohammed, Rabab; Lee, Andrew; Franks, Hester; Kilpatrick, Laura; Yilmazer, Acelya; Paish, E.; Ellis, Ian; Patel, Poulam; Jackson, Andrew

doi:10.1186/bcr2195

IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines

Zhu X., Mulcahy L. A., Mohammed R. A. A., Lee A. H. S., Franks H. A., Kilpatrick L., ...Daha Fazla

BREAST CANCER RESEARCH, cilt.10, sa.6, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 10 Sayı: 6
Basım Tarihi: 2008
Doi Numarası: 10.1186/bcr2195
Dergi Adı: BREAST CANCER RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Ankara Üniversitesi Adresli: Hayır

Özet

Introduction IL-17 plays an important role in autoimmunity, promoting autoimmunity, inflammation and invasion in multiple sclerosis, rheumatoid arthritis and type I diabetes. The role of IL-17 in cancer is unclear, however, as there are few studies examining IL-17 protein expression in cancer. We therefore examined IL-17 protein expression in human breast cancer and modelled its potential biological significance in vitro.