EFFECTS OF CALCITONIN THERAPY ON OSTEOPOROSIS IN PATIENTS WITH THALASSEMIA

CANATAN D., AKAR N., ARCASOY A.

ACTA HAEMATOLOGICA, vol.93, no.1, pp.20-24, 1995 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 93 Issue: 1
  • Publication Date: 1995
  • Doi Number: 10.1159/000204084
  • Journal Name: ACTA HAEMATOLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.20-24
  • Keywords: THALASSEMIA, OSTEOPOROSIS, CALCITONIN, CHILDREN
  • Ankara University Affiliated: No

Abstract

The aim of this study was to evaluate the effects of calcitonin (CT) treatment on bone pain, osteoporosis, bone fractures and blood chemistry in thalassemic patients. Twenty-four patients with an age range of 10-24 years were included, 14 of whom received 100 IU CT and 250 mg calcium 3 times a week. The others (n = 10) were followed up as a control group with only routine thalassemia therapy. After 1 year of treatment, bone pain disappeared and radiological signs of osteoporosis had improved significantly (p < 0.01) in the treatment group. CT has no important side effects.