Akademik Veri Yönetim Sistemi
37th ECNP Congress , Milan, İtalya, 21 - 24 Eylül 2024, cilt.3, sa.2, ss.473-474, (Özet Bildiri)
ntroduction: Internalized stigma in schizophrenia patients significantly affects their well-being.It refers to the process by which individuals with mental illness adopt negative societal attitudes and stereotypes, leading to feelings of shame, low self-esteem, and social withdrawal[1].Understanding the factors contributing to internalized stigma is essential for effective intervention.This study focuses on two key psychological constructs:sense of agency and belief in a just world.The sense of agency is a fundamental mechanism for delineating the self from the environment and others, it reflects individuals' perceived control over their actions[2].The belief in a just world refers to the perception that the world is fair and people get what they deserve[3].This study explores how these factors effect internalized stigma, aiming to develop targeted interventions and improve mental health outcomes. Methods: Fourty-three schizophrenia patients diagnosed according to DSM-5 criteria participated in this study.Remission status was determined using the Positive and Negative Syndrome Scale(PANSS).Internalized stigma was evaluated using the Internalized Stigma of Mental Illness(ISMI) scale with five subscales:alienation, stereotype endorsement, perceived discrimination, social withdrawal, and stigma resistance.Sense of agency was assessed using the Sense of Agency Scale (SoAS) measuring positive(SoAS-P) and negative(SoAS-N) agency perception.Additionally, participants completed the Just World Belief(JBW) scale, consisting of two subtypes:JBW -S(belief in a just world towards self) and JBW-G(belief in a just world for general).Correlation and linear regression analyses were conducted to examine the relationships between ISMI scores, sense of agency, and belief in a just world in schizophrenia patients. Results: 67.4% of the participants were male and 32.6% were female.There were no significant relations between clinical variables and scale scores.Analysis revealed significant positive moderate correlations between SoAS-N and ISMI total and all subscales except stigma resistance, r¼.538, .556, .428, .424, .598 respectively; p< .001 for all.SoAS-P and ISMI total scale, alienation, social withdrawal, and stigma resistance subscales were negatively correlated, r¼- .351,p ¼.021;r ¼-.387,p ¼.010;r¼-.390, p¼.010;r¼-.394;p¼.009.There was a negative correlation between JBW-S and ISMI-perceived discrimination subscale, r¼-.352,p ¼.021. The predicting relationships between ISMI total and subscales and SoAS and JWB were analysed with a linear regression model with independent variables:SoASN, SoAS-P, JBW-S, JBW-G and PANNS-total.The model was significant [F(5,43)¼ 4.58, p¼.002), with an adjusted R2 ¼.29 for ISMI total.These results suggest that %29 of the variances in ISMI-total are predicted by SoAS and JWB scores.Only the SoAS-N subscale significantly added to the model.All other regression modes were significant except for ISMI-resistance for treatment.And SoAS-N was the only robust significant predictor in all these models.
The model was significant [F(5,43)¼3.03,p ¼.022), with an adjusted R2 ¼.19 for ISMI perceived discrimination subscale.In this model, besides SoAS-N, JWB-S subscale significantly added to the model. Conclusion: The study reveals that negative sense of agency is significantly correlated with various aspects of internalized stigma in schizophrenia patients, while positive sense of agency shows a protective effect. JWB-S is negatively correlated with perceived discrimination, indicating its role in mitigating stigma.Regression analysis confirms SoAS-N as a robust predictor of internalized stigma, with JBW-S also contributing significantly. These findings underscore the importance of interventions targeting sense of agency and personal justice beliefs to alleviate internalized stigma in schizophrenia patients. [1] Barlati, S., Morena, D., Nibbio, G., Cacciani, P., Corsini, P., Mosca, A., Deste, G., Accardo, V., Turrina, C., Valsecchi, P., & Vita, A., 2022. Internalized stigma among people with schizophrenia: Relationship with socio-demographic, clinical and medication-related features. Schizophr Res, 243, 364-371. [2] Krugwasser, A. R., Stern, Y., Faivre, N., Harel, E. V., & Salomon, R., 2022. Impaired sense of agency and associated confidence in psychosis. Schizophrenia, 8(1), 32. [3] Weinberg, D., Stevens, G., Peeters, M., Visser, K., Tigchelaar, J., & Finkenauer, C., 2023. The social gradient in adolescent mental health: mediated or moderated by belief in a just world? Eur Child Adolesc Psychiatry, 32(5), 773-782. No conflict of interest https://doi.org/10.1016/j.nsa.2024.105010