Sturge-Weber syndrome: Diffusion magnetic resonance imaging and proton magnetic resonance spectroscopy findings

Cakirer S., Yagmurlu B., Savas M.

ACTA RADIOLOGICA, vol.46, no.4, pp.407-410, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 4
  • Publication Date: 2005
  • Doi Number: 10.1080/02841850510021274
  • Journal Name: ACTA RADIOLOGICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.407-410
  • Keywords: diffusion magnetic resonance imaging, magnetic resonance imaging, brain, proton MR spectroscopy, Sturge-Weber syndrome
  • Ankara University Affiliated: No

Abstract

We report on the diffusion magnetic resonance imaging (MRI) and proton MR spectroscopy findings of a 26-year-old female patient with Sturge-Weber syndrome. Echo-planar trace diffusion MRI revealed mildly high signal intensity changes at parieto-occipital lobes on b=1000 s/mm(2) images, suggesting restricted diffusion. On corresponding apparent diffusion coefficient maps, those areas had moderately high signal intensity and high apparent diffusion coefficient values ( around 0.9610(-3) mm(2)/s) compared with the contralateral symmetrical normal side of the brain (0.776 x 10(-3) mm(2)/s). This finding was consistent with increased motion of water molecules ( disintegration of the neural tissue) in these regions. Proton MR spectroscopy revealed decreased N-acetyl aspartate and increased choline peaks, indicating disintegration of neural tissue associated with neuronal loss as well.