Vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGFR-3 and D2-40 expressions in primary breast cancer: Association with lymph node metastasis

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EROĞLU A., CANSIZ ERSÖZ C., Karasoy D., SAK S.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.26, sa.2, ss.245-249, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.17219/acem/58784
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.245-249
  • Anahtar Kelimeler: breast cancer, metastasis, VEGF, D2-40, FACTOR-C, LYMPHANGIOGENESIS, CARCINOMA, ANGIOGENESIS, PROGNOSIS, DENSITY
  • Ankara Üniversitesi Adresli: Evet

Özet

Background. Two members of the vascular endothelial growth factor (VEGF) family, VEGF-C and -D, are known as lymphangiogenic growth factors and play an important role in tumor lymphangiogenesis via activation of the VEGF receptor (VEGFR)-3, which is expressed in lymphatic endothelial cells. D2-40 is a specific antibody for lymphatic vessel density (LVD).