Ultrastructural view of a promising anti TNF-alpha agent on hepatic ischaemia reperfusion injury

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Kilicoglu B., Kilicoglu S. S., Tuncal S., Onalan A. K., Celepli S., Tasova V., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.116, sa.10, ss.601-607, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4149/bll_2015_117
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.601-607
  • Anahtar Kelimeler: liver, ischemia-reperfusion, liver injury, anti TNF-alpha, TUMOR-NECROSIS-FACTOR, HEME OXYGENASE-1, LIVER, ISCHEMIA/REPERFUSION, INDUCTION, TOLERANCE, CELLS, RATS
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ankara Üniversitesi Adresli: Evet

Özet

BACKGROUND: Ischemia reperfusion causes injury to the liver cells during transplantation, trauma and emergency surgery. We investigated whether the anti TNF-alpha agent, etanercept, can reduce injury in an animal model of ischemia reperfusion owing to the fact that TNF-alpha plays a critical role in the process of inflammation.