Synthesis and antifungal properties of some benzimidazole derivatives

Kilcigil G., Altanlar N.

TURKISH JOURNAL OF CHEMISTRY, vol.30, no.2, pp.223-228, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 2
  • Publication Date: 2006
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.223-228
  • Keywords: benzimidazole, thiourea, antifungal, POTENT ANTIMICROBIAL ACTIVITY, ANTIOXIDANT PROPERTIES, AGENTS, THIOUREA
  • Ankara University Affiliated: Yes

Abstract

Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei. Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 mu g/mL.