Is primary hyperparathyroidism a cause of endothelial dysfunction?

Colak S., Aydogan B. I., Gökçay Canpolat A., Tulunay Kaya C., Şahin M., Çorapçıoğlu D., ...More

CLINICAL ENDOCRINOLOGY, vol.87, no.5, pp.459-465, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 87 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1111/cen.13418
  • Journal Name: CLINICAL ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.459-465
  • Keywords: carotid intima-media thickness, endothelial dysfunction, flow-mediated dilation, primary hyperparathyroidism, vitamin D, INTIMA-MEDIA THICKNESS, MILD PRIMARY HYPERPARATHYROIDISM, CAROTID-ARTERY, BRACHIAL-ARTERY, CARDIOVASCULAR-DISEASE, HEART-DISEASE, ATHEROSCLEROSIS, VASODILATION, INFLAMMATION, IMPROVES
  • Ankara University Affiliated: Yes

Abstract

Objective: Symptomatic primary hyperparathyroidism (PHPT) is thought to be related to increased cardiovascular morbidity and mortality. In our study, we aimed to investigate endothelial dysfunction and markers of subclinical atherosclerosis in patients with PHPT. Also we aimed to demonstrate the effect of vitamin D supplementation on these parameters.