ANCA positive pauci-immune glomerulonephritis as presenting feature of mantle cell lymphoma: A case report and review of literature Glomerulonefritis pauciinmune ANCA positiva como manifestación inicial de linfoma de células del manto: Informe de un caso y revisión de la literatura

KUMRU, GİZEM; YÜKSEL, MERVE; Geriş, Yasemin; YILDIRIM, EMİNE; KİREMİTCİ, SABA; KUZU, IŞINSU; ARSLAN, ÖNDER

doi:10.1016/j.nefroe.2025.501363

ANCA positive pauci-immune glomerulonephritis as presenting feature of mantle cell lymphoma: A case report and review of literature Glomerulonefritis pauciinmune ANCA positiva como manifestación inicial de linfoma de células del manto: Informe de un caso y revisión de la literatura

KUMRU G., YÜKSEL M., Geriş Y., YILDIRIM E. S., KİREMİTCİ S., KUZU I., ...More

Nefrologia, vol.46, no.1, 2026 (Scopus)

Publication Type: Article / Article
Volume: 46 Issue: 1
Publication Date: 2026
Doi Number: 10.1016/j.nefroe.2025.501363
Journal Name: Nefrologia
Journal Indexes: Scopus
Keywords: Anti-neutrophil cytoplasmic antibody, Mantle cell lymphoma, Pauci-immune cresentic glomerulonephritis, Rapidly progressive glomerulonephritis
Ankara University Affiliated: Yes

Abstract

Kidney involvement in mantle cell lymphoma is rare. We report a case of mantle cell lymphoma diagnosed after rapidly progressive glomerulonephritis with biopsy-proven paraneoplastic anti-neutrophil cytoplasmic antibody positive pauci-immune cresentic glomerulonephritis. Lymphoma treatment resulted in improved kidney function. This report demonstrates that pauci-immune cresentic glomerulonephritis can cause kidney impairment as the initial manifestation of mantle cell lymphoma. Physicians should be aware of the atypical presentations of the disease.