Human leucocyte antigens in tympanosclerosis

Dursun G., Acar A., Turgay M., Calguner M.

CLINICAL OTOLARYNGOLOGY, cilt.22, sa.1, ss.62-64, 1997 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 1
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1046/j.1365-2273.1997.00867.x
  • Dergi Adı: CLINICAL OTOLARYNGOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.62-64
  • Anahtar Kelimeler: human leucocyte antigen (HLA), tympanosclerosis, SECRETORY OTITIS, ANKYLOSING-SPONDYLITIS, HLA, ASSOCIATION, INSERTION, GROMMETS, DISEASE, DRUM
  • Ankara Üniversitesi Adresli: Evet

Özet

This study was designed to evaluate the association between certain HLA antigens and tympanosclerosis. The serum concentrations of HLA antigens were measured by a microlymphocytotoxicity technique in patients with tympanosclerosis and compared with a healthy control group. The serum levels of HLA-B35 and -DR3 were significantly higher in the patients with tympanosclerosis. This result suggests that certain types of HLA antigens may play an important role as an indicator or mediator in the pathogenesis of tympanosclerosis.