Selective Immunoglobulin M Deficiency Presenting with Recurrent Impetigo: A Case Report and Review of the Literature

Belgemen T., Suskan E., DOĞU E. F., İKİNCİOĞULLARI K. A.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, cilt.149, sa.3, ss.283-288, 2009 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 149 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1159/000199725
  • Dergi Adı: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.283-288
  • Anahtar Kelimeler: Impetigo, Selective immunoglobulin M deficiency, IGM DEFICIENCY, FUNCTIONAL ASSESSMENT, LYMPHOCYTE-T, ASSOCIATION, CHILDREN
  • Ankara Üniversitesi Adresli: Evet

Özet

Selective immunoglobulin M (IgM) deficiency is a rare disorder defined by a decreased serum level of IgM and normal levels of other immunoglobulin classes. The disease has not been well described and the cause remains unknown. Patients with IgM deficiency may present with a wide spectrum of clinical manifestations, from asymptomatic to life-threatening infections, including recurrent respiratory and gastrointestinal infections, allergy and autoimmunity. Here, we report a 6.5-year-old otherwise healthy boy with selective IgM deficiency who presented with multiple recurrent impetigo. We reviewed the published data regarding selective deficiency of IgM. Copyright (c) 2009 S. Karger AG, Basel