Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus

Algül E., ÖZBEYAZ N. B., Şahan H. F., Aydınyılmaz F., Sunman H., Efe T. H., ...Daha Fazla

Cardiovascular journal of Africa, cilt.36, sa.2, ss.191-195, 2025 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.5830/cvja-2025-021
  • Dergi Adı: Cardiovascular journal of Africa
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.191-195
  • Anahtar Kelimeler: apical thrombus, myocardial infarction, platelet‐to‐haemoglobin ratio
  • Ankara Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients. MATERIALS & METHODS: This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT. RESULTS: PHRwas significantly higher in the AT group (2.03 ± 0.64 vs. 1.85 ± 0.50; p <0.001).Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity. CONCLUSION: PHR is a simple, accessible marker for predicting AT in MI patients. Its use may improve early risk stratification and clinical outcomes.