The effects of the ethanol extract of Cordia myxa leaves on the cognitive function in mice

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Kendir G., Bae H. J., Kim J., Jeong Y., Bae H. J., Park K., ...Daha Fazla

BMC COMPLEMENTARY MEDICINE AND THERAPIES, cilt.22, sa.1, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1186/s12906-022-03693-z
  • Dergi Adı: BMC COMPLEMENTARY MEDICINE AND THERAPIES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Cordia myxa, Alzheimer's disease, Recognition memory, Sensorimotor gating, PI3K-Akt-GSK3 beta signaling, ERK-CREB signaling, ROSMARINIC ACID, ALZHEIMERS-DISEASE, MEDICINAL-PLANTS, MEMORY DEFICITS, IMPAIRMENT, RECEPTOR, ANTIOXIDANT, INHIBITION, INFECTION, L.
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Cordia myxa L. (Boraginaceae) is widely distributed in tropical regions and it's fruits, leaves and stem bark have been utilized in folk medicine for treating trypanosomiasis caused by Trypanosoma cruzi. A populationbased study showed that T. cruzi infection is associated with cognitive impairments. Therefore, if C. myxa has ameliorating activities on cognitive function, it would be useful for both T. cruzi infection and cognitive impairments.