Research Information System
Kardiyovasküler Akademi ve İnternational Academy of Young Cardiologist Congress, Girne, Cyprus (Kktc), 18 - 22 September 2024, pp.14
Background and Aim: It is known that poor immune-nutri5onal status is associated with poor prognosis
in many critical illnesses. It has been shown in the literature, by using different immune parameters, that
poor immune-nutri5onal status is associated with increased mortality and thrombus burden in patients
with myocardial infarc5on. Osaka prognos5c score (OPS), defined as the immune-nutri5onal status
parameter in recent years, has been shown in the literature to be an objective and easily applicable
parameter in showing the prognosis of cancer patients. In our study, we planned to investigate the
relationship of Osaka prognostic score with thrombus burden in patients with ST eleva5on myocardial
infarction (STEMI).
Methods: A total of 925 patients presenting with STEMI were included in this retrospec5ve study. The
patients' baseline demographics, echocardiographic data, and in-hospital follow-up data were obtained
from hospital records. OPS was calculated from the biochemistry samples taken at the 5me of
admission, using CRP, serum albumin and total lymphocyte counts values as defined in the literature.
Coronary thrombus burden was calculated according to the TIMI thrombus classification. Pa5ents with
TIMI thrombus grade <3 were defined as low thrombus burden (LTB) group, and those with TIMI
thrombus grade >=3 were defined as high thrombus burden (HTB) group.
Results:LTB was detected in 576 pa5ents, while HTB was detected in 349 pa5ents. Osaka prognos5c
score was found to be significantly higher in the HTB group. (1.68±0.46 vs. 0.46±0.12; p = 0.002) The
incidence of DM, HT, anterior MI rate and in-hospital mortality rate were also higher in the HTB group
compared to the LTB group.
Conclusion:We found that OSP, which can be easily calculated from patients' baseline laboratory data, is
associated thrombus burden in STEMI patients.