Concentration of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs in human adipose tissue from Turkish men

Cok I., Donmez M. K., Satiroglu M. H., Aydinuraz B., Henkelmann B., Kotalik J., ...More

CHEMOSPHERE, vol.66, no.10, pp.1955-1961, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 10
  • Publication Date: 2007
  • Doi Number: 10.1016/j.chemosphere.2006.07.071
  • Journal Name: CHEMOSPHERE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1955-1961
  • Keywords: polychlorinated dibenzo-p-dioxins and furans, dioxin-like PCBs, HRGC/HRMS, adipose tissue, Turkey, HAZARDOUS-WASTE INCINERATOR, TOXIC EQUIVALENCY FACTORS, GENERAL-POPULATION, ORGANOCHLORINE PESTICIDES, RISK-ASSESSMENT, BIPHENYLS PCBS, PCDD/F, EXPOSURE, COPLANAR, SAMPLES
  • Ankara University Affiliated: No

Abstract

There is no previous report from Turkey on chemically determined polychlorinated dibenzo-para-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs) in human tissues expressed as World Health Organization (WHO) toxic equivalents (TEQs). The objective of this study was to determine the occurrence of PCDDs/Fs, and dioxin-like PCBs in the general adult Turkish population. For this reason we measured adipose tissue concentrations of PCDDs/Fs and dioxin-like PCBs in 23 Turkish men living in Ankara,Turkey in 2004. PCDD/F concentrations ranged between 3.2 and 19.7 pg WHO-TEQ/g fat (5.34 and 42.7 WHO-TEQ/g fat, respectively, including dioxin-like PCBs). The mean concentrations of WHO(PCDD/F-)TEQ and WHO(PCB-)TEQ were 9.2 and 6.67 pg/g on a lipid basis, respectively. Samples were analyzed for PCDD/F and twelve dioxin-like PCB congeners using high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS). This study is very important since it is the first report on PCDDs/Fs and dioxin-like PCB contamination in human adipose tissue from Turkey. (c) 2006 Elsevier Ltd. All rights reserved.