Preparation of Multiwalled Carbon Nanotubes: Electrochemically Treated Pencil Graphite Electrodes for Nanomolar Detection of L-Tryptophan in Complex Samples

Yildiz C., ESKİKÖY BAYRAKTEPE D., YAZAN Z.

CHEMISTRYSELECT, cilt.7, sa.40, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 40
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1002/slct.202201697
  • Dergi Adı: CHEMISTRYSELECT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier
  • Anahtar Kelimeler: Electrochemical pretreatment, L-Tryptophan, multi-walled carbon nanotubes, pencil graphite electrode, voltammetry, URIC-ACID, ASCORBIC-ACID, PASTE ELECTRODE, CAPILLARY-ELECTROPHORESIS, SENSITIVE DETERMINATION, VOLTAMMETRIC SENSOR, DOPAMINE, NANOPARTICLES, TYROSINE, LIQUID
  • Ankara Üniversitesi Adresli: Evet

Özet

The present work reports a sensitive and simple sensor based on an electrochemically treated pencil graphite electrode (pre-PGE) modified with multi-walled carbon nanotubes (MWCNTs) for electrochemical determination of L-tryptophan (L-Try) detection in the presence of uric acid. Electrochemical and physical characterizations of the MWCNTs/pre-PGE were investigated using cyclic voltammetry (CV), Electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM) techniques. Under the optimized conditions, the linear working range was 0.030-200.0 mu M with a limit of detection of 9.0 nM using the differential pulse adsorptive stripping voltammetry (DPAdSV) method. The proposed sensor exhibited good sensitivity, repeatability, reproducibility, and stability. The MWCNTs/pre-PGE were successfully applied to L-Try determination in commercial poly-amino acid supplements with good recovery and accuracy.