Nanostructured Metal Oxide-Based Electrochemical Biosensors in Medical Diagnosis

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Keles G., Sifa Ataman E., Taskin S. B., Polatoglu İ., KURBANOĞLU S.

Biosensors, cilt.14, sa.5, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 14 Sayı: 5
  • Basım Tarihi: 2024
  • Doi Numarası: 10.3390/bios14050238
  • Dergi Adı: Biosensors
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, EMBASE, INSPEC, MEDLINE, Directory of Open Access Journals
  • Anahtar Kelimeler: biosensor, electrochemistry, medical diagnosis, metal oxide nanomaterials, nanostructures
  • Ankara Üniversitesi Adresli: Evet

Özet

Nanostructured metal oxides (NMOs) provide electrical properties such as high surface-to-volume ratio, reaction activity, and good adsorption strength. Furthermore, they serve as a conductive substrate for the immobilization of biomolecules, exhibiting notable biological activity. Capitalizing on these characteristics, they find utility in the development of various electrochemical biosensing devices, elevating the sensitivity and selectivity of such diagnostic platforms. In this review, different types of NMOs, including zinc oxide (ZnO), titanium dioxide (TiO2), iron (II, III) oxide (Fe3O4), nickel oxide (NiO), and copper oxide (CuO); their synthesis methods; and how they can be integrated into biosensors used for medical diagnosis are examined. It also includes a detailed table for the last 10 years covering the morphologies, analysis techniques, analytes, and analytical performances of electrochemical biosensors developed for medical diagnosis.