Effect of Riluzole on Spinal Cord Regeneration with Hemisection Method Before Injury
WORLD NEUROSURGERY, cilt.114, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 114
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.wneu.2018.02.171
- Dergi Adı: WORLD NEUROSURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Neuroprotection, Neuroregeneration, Riluzole, Spinal cord injury, SODIUM-CHANNEL BLOCKERS, VENTRAL ROOT AVULSION, FUNCTIONAL RECOVERY, ISCHEMIA
- Ankara Üniversitesi Adresli: Evet
Özet
OBJECTIVE: The pathophysiology of spinal cord injury (SCI) with the information obtained to date has not been elucidated fully. A safe drug or treatment protocol that results in cell regeneration for SCI remains unknown. Neuroprotective and neuroregenerative effects of riluzole, administered after a SCI, have been shown in experimental studies. This study aimed to investigate the effect of riluzole on neural regeneration in a rat SCI model.