Long-term effects of interferon alpha 2A treatment in Behcet's disease

BOYVAT A., Sisman-Solak C., Gurler A.

DERMATOLOGY, cilt.201, sa.1, ss.40-43, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 201 Sayı: 1
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1159/000018427
  • Dergi Adı: DERMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.40-43
  • Anahtar Kelimeler: Behcet's disease, interferon alpha, THERAPY
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Between May 1995 and April 1996, 20 patients with Behcet's disease were successfully treated with interferon alpha(2a) (IFN-alpha(2a)) 9 million IU/day three times a week and 16 patients with colchicine 1.5 mg/day orally for 3 months. Objective: To study the long-term effects of IFN treatment in Behcet's disease. Methods: Between the years of 1996 and 1999, the patients were followed up every 3 months or whenever indicated. Retrospective evaluation was performed. Results: In 56% of the patients with complete remission or partial remission at the end of IFN-alpha(2a) treatment, long-term remissions ranging from 36 to 48 months were observed. Conclusion: IFN-alpha(2a) treatment is an effective treatment modality in Behcet's disease with the advantage of inducing prolonged remissions. Copyright (C) 2000 S. Karger AG, Basel.