Hutchinson-Gilford progeria syndrome Hutchi̇nson-Gi̇lford progeri̇a sendromu
Turk Geriatri Dergisi, cilt.9, sa.1, ss.42-45, 2006 (Scopus, TRDizin)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 9 Sayı: 1
- Basım Tarihi: 2006
- Dergi Adı: Turk Geriatri Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.42-45
- Anahtar Kelimeler: Hutchinson-Gilford progeria syndrome, Premature aging, Progeria
- Ankara Üniversitesi Adresli: Hayır
Özet
Hutchinson-Gilford progeria syndrome is a premature aging disorder. The syndrome is charecterised by growth reterdasyon and progressive, premature senescent changes of skin, bones and cardiovascular system. Patients usually present between the age of 1 and 2 years with failure to thrive, alopecia and abnormal skin. Death results from cardiovascular changes in the majority of cases. The syndrome is commonly caused by a point mutation in the lamin A gene.