Hutchinson-Gilford progeria syndrome Hutchi̇nson-Gi̇lford progeri̇a sendromu

Pekcan S., ÇOBANOĞLU F. N., Kiper N.

Turk Geriatri Dergisi, cilt.9, sa.1, ss.42-45, 2006 (Scopus) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 9 Sayı: 1
  • Basım Tarihi: 2006
  • Dergi Adı: Turk Geriatri Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.42-45
  • Anahtar Kelimeler: Hutchinson-Gilford progeria syndrome, Premature aging, Progeria
  • Ankara Üniversitesi Adresli: Hayır

Özet

Hutchinson-Gilford progeria syndrome is a premature aging disorder. The syndrome is charecterised by growth reterdasyon and progressive, premature senescent changes of skin, bones and cardiovascular system. Patients usually present between the age of 1 and 2 years with failure to thrive, alopecia and abnormal skin. Death results from cardiovascular changes in the majority of cases. The syndrome is commonly caused by a point mutation in the lamin A gene.