Plasma Amino-Terminal Propeptide of C-Type Natriuretic Peptide Concentration in Normal-Weight and Obese Children

TOPÇU S., ÖZHAN B., ALKAN A., AKYOL M., ORHON F., BAŞKAN S., ...Daha Fazla

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, cilt.9, sa.4, ss.308-314, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/jcrpe.4543
  • Dergi Adı: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.308-314
  • Anahtar Kelimeler: C-type natriuretic peptide, amino-terminal propeptide of C-type natriuretic peptide, obesity, overweight, growth, biomarker, MESENCHYMAL STEM-CELLS, INDUCED CHONDROGENIC DIFFERENTIATION, MASS INDEX REFERENCES, TURKISH CHILDREN, HEALTHY-CHILDREN, LINEAR GROWTH, AGED 6, ADOLESCENTS, OVERWEIGHT, RECEPTOR
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: In studies on the relationship between amino-terminal propeptide of C-type natriuretic peptide (NT-proCNP) concentration and height velocity in children, CNP has been implicated as an emerging new growth marker during childhood. It has been reported that besides its well-studied role in growth, plasma CNP levels are reduced in overweight and/or obese adolescents, suggesting CNP as a potential biomarker in childhood obesity. The primary goal of this study was to test this hypothesis in a Turkish population.