Periodontal treatment of two siblings with juvenile hyaline fibromatosis

Hakki S., Ataoglu T., Avunduk M., Erdemli E., Gunhan O., Rahman N.

JOURNAL OF CLINICAL PERIODONTOLOGY, cilt.32, sa.9, ss.1016-1021, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 9
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1600-051x.2005.00760.x
  • Dergi Adı: JOURNAL OF CLINICAL PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1016-1021
  • Anahtar Kelimeler: capillary morphogenesis protein 2, gingivectomy, histopathologic and electron microscopy, juvenile hyaline fibromatosis, periodontal maintenance, INFANTILE SYSTEMIC HYALINOSIS, SKIN FIBROBLASTS, FOLLOW-UP, MUTATIONS, GENE
  • Ankara Üniversitesi Adresli: Evet

Özet

Background and Aim: Juvenile hyaline fibromatosis (JHF) is an autosomal recessive disease that presents with multiple subcutaneous nodular tumours, gingival fibromatosis, flexion contractures of the joint and hyaline material accumulation in extracellular area. Recently, the causative gene for JHF, capillary morphogenesis protein 2 (CMG2) was identified. In this case report, periodontal status, treatment and follow-up together with histopathologic evaluation of gingival tissue specimens and mutation screening of two JHF cases are presented.