The role of dehydroalanines in enzyme and peptide chemistry


SÜZEN S.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.28, sa.2, ss.129-141, 1999 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 2
  • Basım Tarihi: 1999
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.129-141
  • Anahtar Kelimeler: Antioxidant, Dehydration of serine, Dehydroalanine, Lantibiotic
  • Ankara Üniversitesi Adresli: Evet

Özet

α,β-Dehydroamino acids represent an important class of compound as they are key intermediates in amino acid and peptide synthesis and are constituents of a variety, of naturally occurring antibiotic and phytotoxic peptides including several fungal metabolites which posses antibiotic activity. They also play an important role at the active site of some enzymes and show free radical scavenging activity. It is believed that more detailed investigations are necessary to understand the importance of dehydroalanines.