Antifungal diterpenoids and flavonoids from Ballota inaequidens
PHARMACEUTICAL BIOLOGY, vol.42, no.8, pp.659-663, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 42 Issue: 8
- Publication Date: 2004
- Doi Number: 10.1080/13880200490902626
- Journal Name: PHARMACEUTICAL BIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.659-663
- Keywords: antifungal activity, Ballota inaequidens, ballonigrine, hispanolone, pachypodol, retusin, 5-hydroxy-3,7,4 '-trimethoxyflavone, 5-hydroxy-7,4 '-dimethoxyflavone, 5-hydroxy-3,6,7,4 '-tetramethoxyflavone, 5-hydroxy-7,3,4 '-trimethoxyflavone, SUBSP SAXATILIS, CONSTITUENTS
- Ankara University Affiliated: Yes
Abstract
Two diterpenoids (hispanolone 1, ballonigrine 2) and six flavonoids (5-hydroxy-3,7,4'-trimethoxyflavone 3, retusin 4, 5-hydroxy-7,4'-dimethoxyflavone 5, pachypodol 6, 5-hydroxy-3,6,7,4'-tetramethoxyflavone 7, 5-hydroxy-7,3',4'-trimethoxyflavone 8) have been isolated from the aerial parts of Ballota inaequidens Hub.-Mor. & Patzak. Among them, 7 has not been reported previously in the genus Ballota. The antibacterial and antifungal activities of 1-4, 6, and 8 were tested against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and Candida crusei.