Pregabalin: A New Adjunct in Calcineurin Inhibitor Pain Syndrome Treatment

Tasoglu O., Gokcan H., Demir S. O., Yenigun D., Akdogan M., Kacar S.

PROGRESS IN TRANSPLANTATION, cilt.26, sa.3, ss.224-226, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1177/1526924816654832
  • Dergi Adı: PROGRESS IN TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.224-226
  • Anahtar Kelimeler: organ transplantation, musculoskeletal pain, neuropathic pain, TRANSPLANT PATIENT
  • Ankara Üniversitesi Adresli: Hayır

Özet

Tacrolimus and cyclosporin are calcineurin inhibitors (CIs) commonly used in organ transplants. These agents rarely cause a severe, debilitating pain syndrome of especially lower extremities, known as CI pain syndrome (CIPS). Although the pathogenesis is not well understood, neuropathic pain mechanisms have started to be discussed in the recent literature. Here, presenting a 48-year-old male with CIPS who recovered after pregabalin 150 mg twice daily, we aimed to emphasize the importance of this syndrome and offer a new approach for the treatment. This is the first report in the literature where pregabalin is demonstrated to be effective in CIPS.