Two-layered Au@Ag Bimetallic Nanocomposites-poly (L-Met) Platform for Highly Sensitive Chlorpheniramine Maleate Detection

Bayraktepe D., YAZAN Z.

Electroanalysis, cilt.34, sa.3, ss.445-454, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1002/elan.202100422
  • Dergi Adı: Electroanalysis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, BIOSIS, Chemical Abstracts Core, Chimica, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.445-454
  • Anahtar Kelimeler: Chlorpheniramine maleate, bimetallic nanoparticles, gold and silver nanoparticles, pencil graphite sensor, voltammetry, CARBON-PASTE SENSOR, VOLTAMMETRIC DETERMINATION, ELECTROCHEMICAL DETECTION, NANOPARTICLES, ELECTRODES, DEXTROMETHORPHAN, PSEUDOEPHEDRINE, ASSAY, ACID, FOOD
  • Ankara Üniversitesi Adresli: Evet

Özet

© 2021 Wiley-VCH GmbHThe two-layered bimetallic Au@Ag and poly(L-methionine) (Au@Ag/p-L-met) sensor was newly developed for the electrochemical determination of chlorpheniramine maleate (CPM). After electropolymerization of L-met, bimetallic surfaces were prepared by electrodeposition of Au@Ag nanoparticles on the p-L-met/PGE. The surface characterization was carried out by scanning electron microscopy (SEM), Energy Dispersive X-ray spectroscopy (EDX), Cyclic Voltammetry (CV) and Electrochemical impedance spectroscopy (EIS). The sensor shows good electrocatalytic activity, high sensitivity, wide linear range (0.87–600.0 μM) and a low detection limit (0.26 μM) by using Differential pulse voltammetry (DPV). The sensor was used to determine CPM in pharmaceutical samples with satisfactory results.