Akademik Veri Yönetim Sistemi
Retina-Vitreus, cilt.24, sa.2, ss.119-123, 2016 (Scopus)
© 2015 Gazi Eye Foundation. All Rights Reserved.Purpose: To describe the fundus autofluorescence (FAF) and optical coherence tomography (OCT) findings at adult-onset foveomacular vitelliform dystrophy (AOFVD) and to evaluate their correlation with best corrected visual acuity (BCVA). Material and Methods: The records of 39 eyes were evaluated retrospectively. The BCVA, the findings of fundus examination, OCT and FAF images were noted. Results: Twenty seven (69.2%) of all patients were referred with the diagnosis of age related macular degeneration (AMD). At initial examination 34 (87.1%) eyes presented vitelliform stage and 5 (12.9%) eyes presented the other stages. At last visit 2 (5.1%) eyes progressed to the atrophic stage from the vitelliform stage. At FAF images; we detected well-circumscribed, very high autofluorescence signal in the vitelliform stage, increased autofluorescence with horizontally level in the pseudohypopyon stage, irregular hyperautofluorescence in the vitelliruptive stage and loss of autofluorescence in the atrophic stage. At vitelliform stage 30.7% had patchy, 28.2% focal, 15.3% ring-like, 10.2% round-shape pattern. The correlation between BCVA and FAF patterns could not be shown. At OCT findings; there was a negative correlation between the maximal thickness of the lesion and BCVA, but the correlation between BCVA and maximal width of lesion and central macular thickness could not be shown. There was a negative correlation between presence of IS/OS interface disruption and BCVA. A correlation between subfoveal fluid, RPE alterations and BCVA could not be shown. Conclusions: AOFVD is the most important disorder in the differential diagnosis of AMD. FAF and OCT imaging techniques are useful for confirming the diagnosis of AOFVD. OCT findings are more useful than FAF patterns of the lesions for predicting visual acuity prognosis.