The effect of long term antibiotic treatment on bacteriological cure and somatic cell count at subclinical mastitis due to Staphylococcus aureus in lactating dairy cows


Topuzoglu B., BAŞTAN A., SALAR S.

ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.62, sa.4, ss.289-294, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1501/vetfak_0000002694
  • Dergi Adı: ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.289-294
  • Anahtar Kelimeler: Bacteriological cure, extended treatment, S. aureus, SCC, subclinical mastitis, BOVINE MASTITIS, INTRAMAMMARY, EFFICACY, THERAPY, SUCCESS
  • Ankara Üniversitesi Adresli: Evet

Özet

In this study, the effect of extended antibiotic treatment on bacteriological cure and SCC in lactating dairy cows suffering from subclinical mastitis due to S. aureus was investigated. As material, a total of 100 S. aureus isolated subclinically infected udder lobes were used. Before and after the treatment, milk samples were taken from subclinically infected udder lobes for bacteriological examination and somatic cell counting. Amoxicillin+clavulanic acid combination, determined as sensitive by the antibiogram, was administered both intramammarily and intramuscularly once a day during 7 days to udder lobes infected with S. aureus subclinically. Before treatment and also on 21th day after treatment milk samples were taken aseptically in order to determine bacteriological cure rate and somatic cell counts. At the end of the study, mean SCCs before and after treatment were determined as 300.500 cell/ml (min-max 1.000-992.000 cell/ml) and 183.000 cell/ml (min-max 2.000-6.574.000 cell/ml), respectively. Additionally, the bacteriological cure rate was %66. The difference with regard to mean SCC values between the two samplings was statistically significant (p<0.05). After the treatment, average SCC in S. aureus isolated and non-isolated milk samples were 251.500 cells/ml and 159.500 cell/ml and these differences were not statistically significant. In conclusion, it was determined that long term antibiotic treatment causes an increase at bacteriological cure rate but a decrease at SCC at subclinical mastitis cases due to S. aureus.