PCR investigation of Panton-Valentine leukocidin, enterotoxin, exfoliative toxin, and agr genes in Staphylococcus aureus strains isolated from psoriasis patients

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Gocmen J. S., Sahiner N., Kocak M., KARAHAN Z. C.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.6, ss.1345-1352, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1408-54
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1345-1352
  • Anahtar Kelimeler: Polymerase chain reaction, Staphylococcus aureus, toxin genes, agr typing, SUPERANTIGEN PRODUCTION, IMMUNE EVASION, PROTEIN, INFECTIONS, HOST
  • Ankara Üniversitesi Adresli: Evet

Özet

Background/aim: Staphylococcus aureus colonization is a determiner of disease activation in psoriasis patients. Here we evaluate the presence of genes encoding Panton-Valentine leukocidin (PVL), enterotoxins, TSST-1, exfoliative toxins, and the accessory gene regulatory locus by polymerase chain reaction (PCR) in S. aureus isolates obtained from healthy and diseased skin regions and anterior nares of psoriasis patients and healthy controls.