Antimicrobial activity studies on some morpholinobenzimidazole derivatives Bazi morfoli̇nobenzi̇mi̇dazol türevleri̇ni̇n anti̇mi̇krobi̇yal etki̇leri̇ üzeri̇ne çalişmalar

KUŞ C., ALTANLAR N.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.35, sa.4, ss.237-244, 2006 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 4
  • Basım Tarihi: 2006
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.237-244
  • Anahtar Kelimeler: Antimicrobial effect, Benzimidazole, Inhibition zone diameter
  • Ankara Üniversitesi Adresli: Evet

Özet

In this research, antimicrobial effects of a series of 5-fluoro-2- (substitutedphenyl)-6-morpholino-1H-benzimidazole derivatives have been evaluated against Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Candida albicans. The most active compound 5-fluoro-2-(4-fluorophenyl)-6- morpholino-1H-benzimidazole (7) exhibits 17 mm inhibition zone diameter against C. albicans which is highly similar to that of fluconazole (18 mm).