DEHB’li Çocuklarda Adenozin deaminaz ve Dipeptidil peptidaz aktivitesi

Naralan Y. S., Doğan Ö., Elgün Ülkar S.

39- 32. Ulusal Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları, İstanbul, Türkiye, 10 - 13 Mayıs 2023, ss.228

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: İstanbul
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.228
  • Ankara Üniversitesi Adresli: Evet

Özet

In our study, we aimed to evaluate inflammation by measuring serum Adenosine deaminase (ADA) and dipeptidyl peptidase IV (DPP-IV) activity of individuals diagnosed with attention deficit hyperactivity disorder (ADHD) and to determine its relationship with the Conners Parent Rating Scale- Revised-Long Form (CPRS-R-L) and the Conners Teacher Rating Scale RevisedLong Form (CTRS-R-L). 27 children aged 2-12 years with a diagnosis of attention deficit hyperactivity disorder and 27 children aged 2-12 years without any psychiatric disease were included in the study. Psychiatric examination and clinical evaluation according to K-SADS. The sociodemographic information form, CPRS-R-L for parents and CTRS-R-L for teachers were applied to the patients and the control group who were included in the study. There was no statistically significant difference between the groups in terms of age, gender and sociodemographic data. While serum ADA and DPP-IV activity were found to be statistically significantly higher in the group with ADHD. There was no statistically significant correlation between serum ADA and DPP-IV activities and CTRS-R-L and CPRS-R-L in both groups. We think that T cell mediated inflammation may play a role in the etiology of attention deficit hyperactivity disorder due to changes in ADA and DPP-IV levels in children.