Ophthalmo-acromelic syndrome: Report and review

Tekin M., Tutar E., Arsan S., Atay G., Bodurtha J.

AMERICAN JOURNAL OF MEDICAL GENETICS, cilt.90, sa.2, ss.150-154, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 90 Sayı: 2
  • Basım Tarihi: 2000
  • Dergi Adı: AMERICAN JOURNAL OF MEDICAL GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.150-154
  • Anahtar Kelimeler: ophthalmo-acromelic syndrome, anophthalmia, limb anomalies, autosomal recessive inheritance, absence of inferior vena cava, Waardenburg, INFERIOR VENA-CAVA, RECESSIVE ANOPHTHALMIA, WAARDENBURG, ABNORMALITIES
  • Ankara Üniversitesi Adresli: Evet

Özet

The ophthalmo-acromelic syndrome of Waardenburg is an autosomal recessive trait comprising eye malformations, ranging from true anophthalmia to mild microphthalmia With acromelic malformations, Some 29 affected individuals have been reported since Waardenburg's first, report in 1935 [Waardenburg et al., 1961]. We report on a new case with bilateral anophthalmia and typical limb malformations. The patient also was found to have interruption of the inferior vena cava with azygos continuation as an additional finding. The previous reports are reviewed to elucidate the spectrum of the syndrome. Am. J, Med. Genet. 90:150-154, 2000. (C) 2000 Wiley-Liss, Inc.